Leiomyoma Associated With Epithelial Dysplasia of the Urinary Bladder: Cytopathologic Features and Review of the Literature

Abstract

Leiomyoma of the urinary bladder is a rare benign neoplasm. We report here a unique case of leiomyoma of the urinary bladder in an 82-year-old man. In the urinary bladder, transitional epithelium overlying the submucosal leiomyoma was accompanied with dysplastic changes. Morphological features of the leiomyoma and urothelial dysplasia including cytological characters are shown. Furthermore, the possible relationship between two lesions is also discussed. Present authors speculated that papillomatous nodule caused by the submucosal leiomyoma induced persistent erosive changes which led to creation of newly dysplastic cells through cellular regeneration following epithelial damage.