World Journal of Nephrology and Urology, ISSN 1927-1239 print, 1927-1247 online, Open Access
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Case Report

Volume 14, Number 1, June, pages 22-25

Leiomyoma Associated With Epithelial Dysplasia of the Urinary Bladder: Cytopathologic Features and Review of the Literature

Figures

Figure 1.
Figure 1. Urinary cytology showing a cluster of atypical urothelial cells with increased nuclear/cytoplastic ratio and grooved nuclei (Papanicolaou stain, scale bar = 10 µm).
Figure 2.
Figure 2. A round nodule of leiomyoma with histological features of fascicles of spindle-shaped cells with fusiform nuclei and eosinophilic cytoplasm. Overlying epithelium with erosive changes is present (hematoxylin and eosin stain, scale bar = 50 µm).
Figure 3.
Figure 3. Histology of the surface epithelium with characteristics of urothelial dysplasia. The figure illustrates the loss of the perpendicular arrangement and nuclear abnormality such as enlargement, overlapping or eccentric style (hematoxylin and eosin stain, scale bar = 20 µm).
Figure 4.
Figure 4. High nuclear p53 expression (> 50%) is present in the dysplastic urothelial epithelium (immunohistochemistry of p53, scale bar = 20 µm).